Experimental and Computational Biology[ by Prof. Dr. Röbbe Wünschiers - University of Applied Sciences - Mittweida/Germany ] [research]

"There are no such things as applied sciences, only applications of science" (Louis Pasteur)

Scientific Stations

1996-99 PhD at the University of Marburg/Germany # 1999-2001 PostDoc at Uppsala University in Uppsala/Sweden # 2002-05 PostDoc at the University of Cologne/Germany # 2005-07 Independent Researcher & Lecturer at the University of Cologne/Germany # 2005-06 Guest Lecturer at Marburg University/Germany # 2006 Habilitation in Genetics at the University of Cologne # 2006-07 Guest Lecturer at Bingen University of Applied Sciences/Germany # 2007 - 2009 Bioinformatics Manager at BASF Plant Science subsidiary SunGene GmbH # since 2007 Guest Lecturer at University of Cologne # since September 2009 Professor for Biochemistry/Molecular Biology at University of Applied Sciences Mittweida/Germany

Main Objective

Our research tries to bring knowledge from the lab to the computer and back. The focus lies on the generation and utilisation of nucleic acid data. This is applied to quit diverse fields such as

  • research in the field of biogas production and ecological stoichiometry.
  • development of experimental and computational enabling technologies and tools to facilitate biotechnological utilization of microorganisms.
  • integration, modelling, visualisation, and simulation of genomic metadata.
  • analysis of genetic diversity and dynamics.

Project Summaries

  • Eine deutschsprachige Zusammenfassung ist hier zu finden.
  • The following scheme gives an overview on current research activities:

Anaerobic Digestion

  • Methane is a well established energy carrier that can be generated from organic waste. The goal is to gain understanding of the dynamics of the transcriptome in anaerobic digesters. The obtained data shall facilitate modelling of the process, in particular with respect to changing substrates, in order to optimise methane production.
  • in cooperation with Prof. Dr. Hauke Harms, Uni Leipzig

Hydrogen Producing Bacteria

  • Hydrogen is a powerful and carbon-free energy carrier. It can be produced from water or organic substrates by sunlight powered bacteria. On the basis of genetic strain variations and resulting transcriptome activities we analyse the hydrogen producing capabilities of purple and cyanobacteria.
  • in cooperation with Prof. Dr. Michael Göttfert, TU Dresden

Bio-Composition of Aerosols

  • In-door farming results in concentrated aerosols and exhaust air. This may lead to high local concentrations of pathogenic microorganisms or spores. The goal is to develop novel techniques that help to identify these quickly.
  • in cooperation with Prof. Dr. Michael Göttfert, TU Dresden; PD Dr. Udo Jäckel, Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Berlin; Dr. Henriette Mietke, Staatliche Betriebsgesellschaft für Umwelt und Landwirtschaft, Nossen

Data Integration, Modelling and Visualisation

  • High-throughput technologies in the field of metabolite, protein and nucleic acid analytics leads to large inter-connected datasets. The goal is to develop a platform to integrate and visualise these data and facilitate modelling and simulations.
  • in cooperation with Prof. Dr. Javier F. Urchueguía Schölzel et al., UP Valencia

Classification of Pathogenic Bacteria

  • Tularemia is a disease that is severe and can be transmitted between humans to animals. Together with the Friedrich-Loeffler-Institute we develop a fast, nucleic acid-based classification system for the disease causing sero-strains.
  • in cooperation with PD Dr. Herbert Tomaso et al., Friedrich-Löffler-Institut Jena

Pollen Analysis

  • Bees in agroecosystems are important pollinators for many crops. We investigate the diversity of pollen sources and resulting effect on honey bee and bumble bee behaviour.
  • in cooperation with PD Dr. Catrin Westphal et al., University Göttingen

Hereditary Diseases in Sheep-Poodle

  • The living sheep-poodle population in Germany has a size of around 150 individuals. This increases the risk of inbreeding effects. Together with breeders we try to identify potential hereditary diseases.
  • in cooperation with breeders Nina Borzner, Marburg and Mechthild Jennissen-Tibbe, Oberseifersdorf

Group Members

  • A list of all current group members can be found here.

research.txt · Last modified: 2018/06/05 15:35 by superadmin
Prof. Dr. Röbbe Wünschiers - University of Applied Sciences - Technikumplatz 17 - 09648 Mittweida/Germany - roebbe.wuenschiers|AT|hs-mittweida.de
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